TAIP-12 blocking peptide
TAIP-12 Blocking Peptide
Gene Names
CSRNP2; C12orf2; PPP1R72; TAIP-12; C12orf22; FAM130A1
Applications
Blocking/Control
Purity
The purity is >90%,tested by HPLC and MS.
Synonyms
TAIP-12; TAIP-12 Blocking Peptide; C12ORF22; Chromosome 12 open reading frame 22; CSRN2_HUMAN; CSRNP-2; CSRNP2; Cysteine serine rich nuclear protein 2; Cysteine/serine-rich nuclear protein 2; Family with sequence similarity 130; member A1; Protein FAM130A1; TAIP12; TGF beta induced apoptosis protein 12; TGF-beta-induced apoptosis protein 12; TAIP-12 blocking peptide
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Applicable Applications for TAIP-12 blocking peptide
Blocking/Control
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TAIP-12 blocking peptide
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,591 Da
NCBI Official Full Name
cysteine/serine-rich nuclear protein 2
NCBI Official Synonym Full Names
cysteine-serine-rich nuclear protein 2
NCBI Official Symbol
CSRNP2
NCBI Official Synonym Symbols
C12orf2; PPP1R72; TAIP-12; C12orf22; FAM130A1
NCBI Protein Information
cysteine/serine-rich nuclear protein 2; CSRNP-2; TGF-beta-induced apoptosis protein 12; protein phosphatase 1, regulatory subunit 72; family with sequence similarity 130, member A1
UniProt Protein Name
Cysteine/serine-rich nuclear protein 2
UniProt Gene Name
CSRNP2
UniProt Synonym Gene Names
C12orf22; FAM130A1; TAIP12; CSRNP-2; TAIP-12
UniProt Entry Name
CSRN2_HUMAN
NCBI Description
The protein encoded by this gene belongs to the CSRNP family of nuclear proteins that share conserved regions, including cysteine- and serine- rich regions, a basic domain, a transcriptional activation domain, and bind the sequence 'AGAGTG', thus have the hallmark of transcription factors. Studies in mice suggest that these genes may have redundant functions. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
TAIP12: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis. Belongs to the AXUD1 family.
Chromosomal Location of Human Ortholog: 12q13.11-q13.12
Cellular Component: nucleus
Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity; phosphatase binding
Biological Process: transcription, DNA-dependent; apoptosis; positive regulation of transcription from RNA polymerase II promoter
