TAF7L blocking peptide

TAF7L Blocking Peptide (N-term)

• Gene Names: TAF7L; CT40; TAF2Q
• Synonyms: TAF7L; TAF7L Blocking Peptide (N-term); Transcription initiation factor TFIID subunit 7-like; Cancer/testis antigen 40; CT40; RNA polymerase II TBP-associated factor subunit Q; TATA box-binding protein-associated factor 50 kDa; Transcription initiation factor TFIID 50 kDa subunit; TAF2Q; TAF7L blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 462

• Cellular Location: Nucleus. Cytoplasm. Note: Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
• Tissue Location: Testis-specific.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TAF7L blocking peptide

Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 74762183
• NCBI GeneID: 54457
• UniProt Accession #: Q5H9L4; Q5H9L6; Q86XI4; Q9BXU5; Q9H5R0
• Molecular Weight: 34,726 Da
• NCBI Official Full Name: Transcription initiation factor TFIID subunit 7-like
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor 7 like
• NCBI Official Symbol: TAF7L
• NCBI Official Synonym Symbols: CT40; TAF2Q
• NCBI Protein Information: transcription initiation factor TFIID subunit 7-like
• UniProt Protein Name: Transcription initiation factor TFIID subunit 7-like
• Protein Family: Transcription initiation factor
• UniProt Gene Name: TAF7L
• UniProt Synonym Gene Names: TAF2Q; CT40
• UniProt Entry Name: TAF7L_HUMAN

NCBI Description

This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Uniprot Description

TAF7L: Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis. Belongs to the TAF7 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); DNA-binding

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: transcription factor TFIID complex

Molecular Function: histone acetyltransferase binding; transcription coactivator activity; transcription factor binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcriptional preinitiation complex assembly