SYTL5 blocking peptide

SYTL5 Peptide

Cat. Num. AAA152828

• Gene Names: SYTL5; slp5
• Applications: Blocking (BL)
• Synonyms: SYTL5; SYTL5 Peptide; slp5; SLP5; Synaptotagmin-like protein 5; synaptotagmin-like 5; SYTL5 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 730

• Applicable Applications for SYTL5 blocking peptide: Blocking (BL)
• Application Notes: SYTL5 peptide is used for blocking the activity of SYTL5 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 17 amino acids near the amino terminus of human SYTL5.
• Preparation and Storage: Store SYTL5 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 254039650
• NCBI GeneID: 94122
• NCBI Accession #: NP_620135
• NCBI GenBank Nucleotide #: NM_001163335.1
• UniProt Accession #: Q8TDW5; A2RRF2
• Molecular Weight: 83,918 Da
• NCBI Official Full Name: synaptotagmin-like protein 5 isoform 1
• NCBI Official Synonym Full Names: synaptotagmin-like 5
• NCBI Official Symbol: SYTL5
• NCBI Official Synonym Symbols: slp5
• NCBI Protein Information: synaptotagmin-like protein 5; exophilin 9
• UniProt Protein Name: Synaptotagmin-like protein 5
• Protein Family: Synaptotagmin-like protein
• UniProt Gene Name: SYTL5
• UniProt Synonym Gene Names: SLP5
• UniProt Entry Name: SYTL5_HUMAN

NCBI Description

The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

SYTL5: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: membrane

Molecular Function: protein binding; metal ion binding; Rab GTPase binding

Biological Process: intracellular protein transport; exocytosis