SYTL1 blocking peptide

SYTL1 Antibody (Center) Blocking peptide

• Gene Names: SYTL1; JFC1; SLP1
• Synonyms: SYTL1; SYTL1 Antibody (Center) Blocking peptide; Synaptotagmin-like protein 1; Exophilin-7; Protein JFC1; SLP1; SYTL1 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 562

• Cellular Location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note: Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes
• Tissue Location: Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SYTL1 blocking peptide

May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 33301659
• NCBI GeneID: 84958
• UniProt Accession #: Q8IYJ3; Q5SSC9; Q96BB6; Q96GU6; Q96S89; Q96SI0
• Molecular Weight: 60,635 Da
• NCBI Official Full Name: Synaptotagmin-like protein 1
• NCBI Official Synonym Full Names: synaptotagmin like 1
• NCBI Official Symbol: SYTL1
• NCBI Official Synonym Symbols: JFC1; SLP1
• NCBI Protein Information: synaptotagmin-like protein 1
• UniProt Protein Name: Synaptotagmin-like protein 1
• Protein Family: Synaptotagmin-like protein
• UniProt Gene Name: SYTL1
• UniProt Synonym Gene Names: SLP1
• UniProt Entry Name: SYTL1_HUMAN

Uniprot Description

SYTL1: May play a role in vesicle trafficking. Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: extrinsic to plasma membrane; melanosome; plasma membrane

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; neurexin binding; protein binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis of neurotransmitter; exocytosis; regulation of calcium ion-dependent exocytosis; vesicle fusion