STX8 blocking peptide

STX8 Antibody (N-term) Blocking peptide

• Gene Names: STX8; CARB
• Synonyms: STX8; STX8 Antibody (N-term) Blocking peptide; Syntaxin-8; STX8 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 236

• Cellular Location: Membrane; Single-pass type IV membrane protein. Note: Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits (By similarity)
• Tissue Location: Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for STX8 blocking peptide

Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.

NCBI and Uniprot Product Information

• NCBI GI #: 9297054
• NCBI GeneID: 9482
• UniProt Accession #: Q9UNK0; O60712; Q53XT8
• Molecular Weight: 26,907 Da
• NCBI Official Full Name: Syntaxin-8
• NCBI Official Synonym Full Names: syntaxin 8
• NCBI Official Symbol: STX8
• NCBI Official Synonym Symbols: CARB
• NCBI Protein Information: syntaxin-8
• UniProt Protein Name: Syntaxin-8
• Protein Family: Syntaxin
• UniProt Gene Name: STX8
• UniProt Entry Name: STX8_HUMAN

NCBI Description

The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

STX8: Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. Belongs to the syntaxin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p12

Cellular Component: early endosome; endoplasmic reticulum; endosome; integral to plasma membrane; late endosome; perinuclear region of cytoplasm; recycling endosome; SNARE complex; trans-Golgi network; vesicle

Molecular Function: chloride channel inhibitor activity; protein binding; SNAP receptor activity; syntaxin binding

Biological Process: early endosome to late endosome transport; intracellular protein transport; transport; vesicle docking; vesicle fusion