STX1B blocking peptide
STX1B Blocking Peptide (Center)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]
Uniprot Description
STX1B: a type IV membrane protein that may be involved in docking of synaptic vesicles at presynaptic active zones.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: cytosol; integral to membrane; membrane; plasma membrane; SNARE complex; synaptic vesicle
Molecular Function: protein kinase binding; SNAP receptor activity; SNARE binding
Biological Process: intracellular protein transport; positive regulation of neurotransmitter secretion; regulation of gene expression; synaptic vesicle docking during exocytosis; synaptic vesicle fusion to presynaptic membrane; vesicle docking
Disease: Generalized Epilepsy With Febrile Seizures Plus, Type 9
Research Articles on STX1B
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Product Notes
The STX1B stx1b (Catalog #AAA9229319) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STX1B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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