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SMCP blocking peptide

SMCP Antibody (C-term) Blocking peptide

Gene Names
SMCP; MCS; MCSP; HSMCSGEN1
Synonyms
SMCP; SMCP Antibody (C-term) Blocking peptide; Sperm mitochondrial-associated cysteine-rich protein; MCS; MCSP; SMCP blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
116
Cellular Location
Cytoplasm. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Note: Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis
Tissue Location
Testis. Is selectively expressed in the spermatids of seminiferous tubules.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SMCP blocking peptide
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
12,767 Da
NCBI Official Full Name
Sperm mitochondrial-associated cysteine-rich protein
NCBI Official Synonym Full Names
sperm mitochondria associated cysteine rich protein
NCBI Official Symbol
SMCP
NCBI Official Synonym Symbols
MCS; MCSP; HSMCSGEN1
NCBI Protein Information
sperm mitochondrial-associated cysteine-rich protein
UniProt Protein Name
Sperm mitochondrial-associated cysteine-rich protein
UniProt Gene Name
SMCP
UniProt Synonym Gene Names
MCS; MCSP
UniProt Entry Name
MCSP_HUMAN

NCBI Description

Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008]

Uniprot Description

SMCP: Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cytoplasm; mitochondrion

Molecular Function: protein binding

Biological Process: penetration of zona pellucida; sperm motility

Research Articles on SMCP

Similar Products

Product Notes

The SMCP smcp (Catalog #AAA9219433) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SMCP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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