SLC6A14 blocking peptide

SLC6A14 Antibody (C-term) Blocking peptide

• Gene Names: SLC6A14; BMIQ11
• Synonyms: SLC6A14; SLC6A14 Antibody (C-term) Blocking peptide; Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); Amino acid transporter ATB0+; Solute carrier family 6 member 14; SLC6A14 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 642

• Cellular Location: Membrane; Multi-pass membrane protein.
• Tissue Location: Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SLC6A14 blocking peptide

Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner.

NCBI and Uniprot Product Information

• NCBI GI #: 41018156
• NCBI GeneID: 11254
• UniProt Accession #: Q9UN76; Q5H942
• Molecular Weight: 72,153 Da
• NCBI Official Full Name: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
• NCBI Official Synonym Full Names: solute carrier family 6 member 14
• NCBI Official Symbol: SLC6A14
• NCBI Official Synonym Symbols: BMIQ11
• NCBI Protein Information: sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
• UniProt Protein Name: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
• Protein Family: Sodium- and chloride-dependent neutral and basic amino acid transporter
• UniProt Gene Name: SLC6A14
• UniProt Entry Name: S6A14_HUMAN

NCBI Description

This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]

Uniprot Description

SLC6A14: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane; vesicle

Molecular Function: amino acid transmembrane transporter activity

Biological Process: amino acid metabolic process; amino acid transport; response to toxin; transport

Disease: Body Mass Index Quantitative Trait Locus 11