SLC38A8 blocking peptide

SLC38A8 Antibody (Center) Blocking peptide

• Gene Names: SLC38A8; FVH2
• Synonyms: SLC38A8; SLC38A8 Antibody (Center) Blocking peptide; Putative sodium-coupled neutral amino acid transporter 8; Solute carrier family 38 member 8; SLC38A8 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 435

• Cellular Location: Membrane; Multi-pass membrane protein
• Tissue Location: Expressed in fetal and adult brain, and spinal cord. In the brain, it is localized in the cell body and axon of the majority of neuronal cells and in a subset of glial cells Found throughout the neuronal retina, with higher expression levels in the inner and outer plexiform layers and the photoreceptor layer. Very weak expression is also present in the kidneys, thymus, and testes.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SLC38A8 blocking peptide

Putative sodium-dependent amino acid/proton antiporter.

NCBI and Uniprot Product Information

• NCBI GI #: 172049024
• NCBI GeneID: 146167
• UniProt Accession #: A6NNN8
• NCBI Official Full Name: Putative sodium-coupled neutral amino acid transporter 8
• NCBI Official Synonym Full Names: solute carrier family 38 member 8
• NCBI Official Symbol: SLC38A8
• NCBI Official Synonym Symbols: FVH2
• NCBI Protein Information: putative sodium-coupled neutral amino acid transporter 8
• UniProt Protein Name: Putative sodium-coupled neutral amino acid transporter 8
• Protein Family: Putative sodium-coupled neutral amino acid transporter
• UniProt Gene Name: SLC38A8
• UniProt Entry Name: S38A8_HUMAN

NCBI Description

This gene encodes a putative sodium-dependent amino-acid/proton antiporter. The protein has eleven transmembrane domains, an extracellular N-terminus and an intracellular C-terminal tail. The protein is a member of the SLC38 sodium-coupled neutral amino acid transporter family of proteins. Mutations in this gene result in foveal hypoplasia with or without optic nerve misrouting and/or anterior segment dysgenesis. [provided by RefSeq, May 2014]

Uniprot Description

SLC38A8: Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q23.3

Molecular Function: amino acid transmembrane transporter activity

Disease: Foveal Hypoplasia 2