sh3bp4a blocking peptide
sh3bp4a Blocking Peptide (N-term)
Gene Names
sh3bp4a; sh3bp4
Synonyms
sh3bp4a; sh3bp4a Blocking Peptide (N-term); SH3 domain-binding protein 4-A; sh3bp4; sh3bp4a blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 132-145 of HUMAN sh3bp4a
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
965
Cellular Location
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle Nucleus. Note: Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin- coated vesicles. May also localize to the nucleus (By similarity)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for sh3bp4a blocking peptide
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
108,453 Da
NCBI Official Full Name
SH3 domain-binding protein 4-A
NCBI Official Synonym Full Names
SH3-domain binding protein 4a
NCBI Official Symbol
sh3bp4a
NCBI Official Synonym Symbols
sh3bp4
NCBI Protein Information
SH3 domain-binding protein 4-A
UniProt Protein Name
SH3 domain-binding protein 4-A
Protein Family
UniProt Gene Name
sh3bp4a
UniProt Synonym Gene Names
sh3bp4
UniProt Entry Name
SH34A_DANRE
Uniprot Description
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy ().
Similar Products
Product Notes
The sh3bp4a sh3bp4a (Catalog #AAA9229710) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "sh3bp4a, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
