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Western Blot (WB) (Western blot analysis of SAMHD1 in Daudi cell lysate with SAMHD1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

SAMHD1 blocking peptide

SAMHD1 Peptide

Gene Names
SAMHD1; DCIP; CHBL2; HDDC1; MOP-5; SBBI88
Applications
Blocking (BL)
Synonyms
SAMHD1; SAMHD1 Peptide; SAM domain and HD domain 1; DCIP; CHBL2; HDDC1; MOP-5; SBBI88 ; SAMHD1 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
626
Applicable Applications for SAMHD1 blocking peptide
Blocking (BL)
Application Notes
SAMHD1 peptide is used for blocking the activity of SAMHD1 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
18 amino acid peptide near the carboxy terminus of human SAMHD1.
Preparation and Storage
Store SAMHD1 peptide at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of SAMHD1 in Daudi cell lysate with SAMHD1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of SAMHD1 in Daudi cell lysate with SAMHD1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,122 Da
NCBI Official Full Name
deoxynucleoside triphosphate triphosphohydrolase SAMHD1
NCBI Official Synonym Full Names
SAM domain and HD domain 1
NCBI Official Symbol
SAMHD1
NCBI Official Synonym Symbols
DCIP; CHBL2; HDDC1; MOP-5; SBBI88
NCBI Protein Information
deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; monocyte protein 5; dendritic cell-derived IFNG-induced protein; SAM domain and HD domain-containing protein 1
UniProt Protein Name
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Gene Name
SAMHD1
UniProt Synonym Gene Names
MOP5; dNTPase; DCIP; MOP-5
UniProt Entry Name
SAMH1_HUMAN

NCBI Description

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

Uniprot Description

SAMHD1: a protein induced by interferon gamma.

Protein type: EC 3.1.4.-

Chromosomal Location of Human Ortholog: 20pter-q12

Cellular Component: nucleoplasm; plasma membrane; intracellular; nucleus

Molecular Function: protein binding; nucleic acid binding; dGTPase activity; zinc ion binding; RNA binding; dGTP binding

Biological Process: dGTP catabolic process; dATP catabolic process; cytokine and chemokine mediated signaling pathway; immune response; defense response to virus; protein homotetramerization; regulation of innate immune response

Disease: Chilblain Lupus 2; Aicardi-goutieres Syndrome 5

Research Articles on SAMHD1

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Product Notes

The SAMHD1 samhd1 (Catalog #AAA154030) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SAMHD1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). SAMHD1 peptide is used for blocking the activity of SAMHD1 antibody. Researchers should empirically determine the suitability of the SAMHD1 samhd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAMHD1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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