RHEBL1 blocking peptide

RHEBL1 Antibody (N-term) Blocking peptide

• Gene Names: RHEBL1; RHEBL1c
• Synonyms: RHEBL1; RHEBL1 Antibody (N-term) Blocking peptide; GTPase RhebL1; Ras homolog enriched in brain like-1 c; RhebL1c; Ras homolog enriched in brain-like protein 1; Rheb-like protein 1; Rheb2; RHEBL1 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 183

• Cellular Location: Endomembrane system; Lipid-anchor; Cytoplasmic side Cytoplasm
• Tissue Location: Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for RHEBL1 blocking peptide

Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.

NCBI and Uniprot Product Information

• NCBI GI #: 74730357
• NCBI GeneID: 121268
• UniProt Accession #: Q8TAI7; Q56VH8
• Molecular Weight: 8,176 Da
• NCBI Official Full Name: GTPase RhebL1
• NCBI Official Synonym Full Names: Ras homolog enriched in brain like 1
• NCBI Official Symbol: RHEBL1
• NCBI Official Synonym Symbols: RHEBL1c
• NCBI Protein Information: GTPase RhebL1
• UniProt Protein Name: GTPase RhebL1
• Protein Family: GTPase
• UniProt Gene Name: RHEBL1
• UniProt Synonym Gene Names: RhebL1c; Rheb-like protein 1
• UniProt Entry Name: REBL1_HUMAN

Uniprot Description

RHEBL1: Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. Belongs to the small GTPase superfamily. Rheb family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric, Rheb; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: cytoplasm

Molecular Function: GTP binding; protein binding

Biological Process: activation of NF-kappaB transcription factor; TOR signaling pathway