RASSF6 blocking peptide

RASSF6 Peptide

Cat. Num. AAA151875

• Applications: Blocking (BL)
• Synonyms: RASSF6; RASSF6 Peptide; Ras association domain-containing protein 6; Ras association (RalGDS/AF-6) domain family member 6; RASSF6 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 369

• Applicable Applications for RASSF6 blocking peptide: Blocking (BL)
• Application Notes: RASSF6 peptide is used for blocking the activity of RASSF6 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 14 amino acids near the center of human RASSF6.
• Preparation and Storage: Store RASSF6 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 41393610
• NCBI GeneID: 166824
• NCBI Accession #: NP_803876
• NCBI GenBank Nucleotide #: NM_201431.2
• UniProt Accession #: Q6ZTQ3; Q68DT2; Q6PDA6; Q86WG9; Q86WH0
• Molecular Weight: 35,809 Da
• NCBI Official Full Name: ras association domain-containing protein 6 isoform b
• NCBI Official Synonym Full Names: Ras association (RalGDS/AF-6) domain family member 6
• NCBI Official Symbol: RASSF6
• NCBI Protein Information: ras association domain-containing protein 6; putative RAS binding protein; Ras association (RalGDS/AF-6) domain family 6
• UniProt Protein Name: Ras association domain-containing protein 6
• Protein Family: Ras association domain-containing protein
• UniProt Gene Name: RASSF6
• UniProt Entry Name: RASF6_HUMAN

NCBI Description

This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Uniprot Description

RASSF6: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4q13.3

Molecular Function: protein binding

Biological Process: positive regulation of apoptosis; apoptosis; signal transduction