RAP2A blocking peptide
RAP2A Antibody
NCBI and Uniprot Product Information
Uniprot Description
RAP2A: Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. Belongs to the small GTPase superfamily. Ras family.
Protein type: G protein, monomeric; G protein; G protein, monomeric, Ras
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: recycling endosome; recycling endosome membrane; plasma membrane; midbody; cytosol
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: microvillus biogenesis; establishment of protein localization; metabolic process; regulation of dendrite morphogenesis; actin cytoskeleton reorganization; establishment of epithelial cell polarity; positive regulation of protein amino acid phosphorylation; positive regulation of protein amino acid autophosphorylation; negative regulation of cell migration; regulation of JNK cascade; Rap protein signal transduction
Research Articles on RAP2A
Similar Products
Product Notes
The RAP2A rap2a (Catalog #AAA9633304) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RAP2A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
