PLXDC1 blocking peptide
PLXDC1 Antibody(C-term) Blocking peptide
Gene Names
PLXDC1; TEM3; TEM7
Synonyms
PLXDC1; PLXDC1 Antibody(C-term) Blocking peptide; Plexin domain-containing protein 1; Tumor endothelial marker 3; Tumor endothelial marker 7; TEM3; TEM7; PLXDC1 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
500
Cellular Location
Isoform 1: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note: Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells Isoform 3: Secreted.
Tissue Location
Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PLXDC1 blocking peptide
Plays a critical role in endothelial cell capillary morphogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
47,895 Da
NCBI Official Full Name
Plexin domain-containing protein 1
NCBI Official Synonym Full Names
plexin domain containing 1
NCBI Official Symbol
PLXDC1
NCBI Official Synonym Symbols
TEM3; TEM7
NCBI Protein Information
plexin domain-containing protein 1
UniProt Protein Name
Plexin domain-containing protein 1
Protein Family
UniProt Gene Name
PLXDC1
UniProt Synonym Gene Names
TEM3; TEM7
UniProt Entry Name
PLDX1_HUMAN
Uniprot Description
PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: receptor complex
Molecular Function: protein binding
Research Articles on PLXDC1
Similar Products
Product Notes
The PLXDC1 plxdc1 (Catalog #AAA9224306) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PLXDC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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