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PLRG1 blocking peptide

PLRG1 Antibody (N-term) Blocking Peptide

Gene Names
PLRG1; Cwc1; PRL1; PRP46; PRPF46; TANGO4
Synonyms
PLRG1; PLRG1 Antibody (N-term) Blocking Peptide; Pleiotropic regulator 1; PLRG1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
514
Cellular Location
Nucleus. Nucleus speckle.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PLRG1 blocking peptide
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
56,290 Da
NCBI Official Full Name
Pleiotropic regulator 1
NCBI Official Synonym Full Names
pleiotropic regulator 1
NCBI Official Symbol
PLRG1
NCBI Official Synonym Symbols
Cwc1; PRL1; PRP46; PRPF46; TANGO4
NCBI Protein Information
pleiotropic regulator 1
UniProt Protein Name
Pleiotropic regulator 1
Protein Family
UniProt Gene Name
PLRG1
UniProt Entry Name
PLRG1_HUMAN

NCBI Description

This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Uniprot Description

PLRG1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Belongs to the WD repeat PRL1/PRL2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA splicing; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 4q31.2-q32.1

Cellular Component: DNA replication factor A complex; nuclear membrane; nucleolus; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: nuclear mRNA splicing, via spliceosome

Research Articles on PLRG1

Similar Products

Product Notes

The PLRG1 plrg1 (Catalog #AAA9222004) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PLRG1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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