PLEKHF2 blocking peptide
PLEKHF2 Antibody (Center) Blocking Peptide
Gene Names
PLEKHF2; EAPF; PHAFIN2; ZFYVE18
Synonyms
PLEKHF2; PLEKHF2 Antibody (Center) Blocking Peptide; Pleckstrin homology domain-containing family F member 2; PH domain-containing family F member 2; Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; EAPF; PH and FYVE domain-containing protein 2; Phafin-2; Phafin2; Zinc finger FYVE domain-containing protein 18; ZFYVE18; PLEKHF2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
249
Cellular Location
Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note: Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467).
Tissue Location
Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PLEKHF2 blocking peptide
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
27,798 Da
NCBI Official Full Name
Pleckstrin homology domain-containing family F member 2
NCBI Official Synonym Full Names
pleckstrin homology and FYVE domain containing 2
NCBI Official Symbol
PLEKHF2
NCBI Official Synonym Symbols
EAPF; PHAFIN2; ZFYVE18
NCBI Protein Information
pleckstrin homology domain-containing family F member 2
UniProt Protein Name
Pleckstrin homology domain-containing family F member 2
Protein Family
UniProt Gene Name
PLEKHF2
UniProt Synonym Gene Names
ZFYVE18; PH domain-containing family F member 2; EAPF; Phafin2
UniProt Entry Name
PKHF2_HUMAN
Uniprot Description
PLEKHF2: a protein containing a PH domain and a FYVE zinc finger domain.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 8q22.1
Cellular Component: transport vesicle
Molecular Function: protein binding
Research Articles on PLEKHF2
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Product Notes
The PLEKHF2 plekhf2 (Catalog #AAA9222033) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PLEKHF2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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