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PIGU blocking peptide

PIGU Blocking Peptide (N-Term)

Gene Names
PIGU; GAB1; CDC91L1
Synonyms
PIGU; PIGU Blocking Peptide (N-Term); Phosphatidylinositol glycan anchor biosynthesis class U protein; Cell division cycle protein 91-like 1; Protein CDC91-like 1; GPI transamidase component PIG-U; CDC91L1; PIGU blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 122-134 of HUMAN PIGU
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
435
Cellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PIGU blocking peptide
Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
47,611 Da
NCBI Official Full Name
Phosphatidylinositol glycan anchor biosynthesis class U protein
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis class U
NCBI Official Symbol
PIGU
NCBI Official Synonym Symbols
GAB1; CDC91L1
NCBI Protein Information
phosphatidylinositol glycan anchor biosynthesis class U protein
UniProt Protein Name
Phosphatidylinositol glycan anchor biosynthesis class U protein
Protein Family
UniProt Gene Name
PIGU
UniProt Synonym Gene Names
CDC91L1; Protein CDC91-like 1
UniProt Entry Name
PIGU_HUMAN

NCBI Description

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

PIGU: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. Belongs to the PIGU family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; integral to endoplasmic reticulum membrane; membrane; plasma membrane

Molecular Function: GPI-anchor transamidase activity

Biological Process: attachment of GPI anchor to protein; GPI anchor biosynthetic process; regulation of JAK-STAT cascade

Research Articles on PIGU

Similar Products

Product Notes

The PIGU pigu (Catalog #AAA9230423) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PIGU, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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