PHF3 blocking peptide
PHF3 (D2033) Peptide
Applications
Blocking
Purity
Synthetic peptide PHF3 (D2033). (Note: the amino acid sequence is proprietary).The purity is >98%.
Synonyms
PHF3; PHF3 (D2033) Peptide; PHD finger protein 3; PHF3 blocking peptide
Specificity
This peptide can be used with studies using MBS3013729 PHF3 (D2033) pAb.
Purity/Purification
Synthetic peptide PHF3 (D2033). (Note: the amino acid sequence is proprietary).
The purity is >98%.
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
2039
Applicable Applications for PHF3 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for PHF3 blocking peptide
PHF3 (PHD finger protein 3) is a 2039 amino acid ubiquitously expressed protein that is phosphorylated upon DNA damage by either ATM or ATR. PHF3 contains a PHD finger motif, a proline-rich region, a TFIIS domain and two bipartite nuclear localization signals. Since these motifs are frequently found in proteins involved in transcription, PHF3 may function as a transcription factor. Expression of PHF3 is significantly reduced in anaplastic astrocytomas, glioblastomas and glioblastoma cell lines, suggesting that PHF3 plays a role as a tumor suppressor. Antibodies against PHF3 are present in some patients afflicted with glioblastoma multiforme and presence of the, correlates to significantly better survival rates. There are two isoforms of PHF3 that are produced as a result of alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
PHD finger protein 3 isoform 1
UniProt Protein Name
PHD finger protein 3
Protein Family
UniProt Gene Name
PHF3
UniProt Synonym Gene Names
KIAA0244
UniProt Entry Name
PHF3_HUMAN
Uniprot Description
PHF3: a ubiquitous protein containing a PHD domain, TFIIS domain, and SPOC domain, all of which are characteristic of transcription factors. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas. Two alternatively spliced isoforms have been described.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 6q12
Cellular Component: nucleus
Molecular Function: zinc ion binding
Biological Process: transcription, DNA-dependent; multicellular organismal development
Similar Products
Product Notes
The PHF3 phf3 (Catalog #AAA3013730) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PHF3 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the PHF3 phf3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PHF3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
