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PGCG blocking peptide

PGCG Peptide

Applications
Immunodepletion, Immunocompetition
Synonyms
PGCG; PGCG Peptide; CYGF; GC F; guanylate cyclase 2D-like; membrane (retina-specific); Guanylate cyclase 2F; GUC2DL; GUC2F; Gucy2f; RETGC-2; retinal; Rod outer segment membrane guanylate cyclase 2; ROS-GC2 antibody; PGCG blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
3484
Applicable Applications for PGCG blocking peptide
Immunodepletion, Immunocompetition
Application Notes
Confocal Microscopy||1:200
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500
Immunogen
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase G protein.
Expression
Expressed in lung, kidney and skeletal muscle. Low levels in intestine.
Molecular Function
Lyase, Receptor
Structure
Homodimer or heterodimer with NPR1.
Subcellular Location
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm
Preparation and Storage
-20 degree C for long term storage
Related Product Information for PGCG blocking peptide
Antigenic Blocking Peptide Guanylyl Cyclase G
Binds to a yet not identified ligand.
Possible role in processes such as water and electrolyte balance, and muscle contraction.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
48,319 Da
NCBI Official Full Name
Rattus norvegicus guanylyl cyclase-G (GC-G) mRNA, complete cds
UniProt Protein Name
Guanylate cyclase 2G
UniProt Gene Name
Gucy2g
UniProt Synonym Gene Names
Ksgc; GC-G; ksGC
UniProt Entry Name
GUC2G_RAT

Uniprot Description

Gucy2g: a receptor with two intracellular enzymatic activities: a protein kinase of the RGC group and a guanylyl cyclase of the adenylyl cyclase class-4/guanylyl cyclase family. Probably plays a specific functional role in the testis by binding to yet not identified ligand.

Protein type: Lyase; Membrane protein, integral; Guanylyl cyclase; EC 4.6.1.2

Cellular Component: external side of plasma membrane; guanylate cyclase complex, soluble; integral to membrane; intracellular; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; GTP binding; guanylate cyclase activity; protein kinase activity

Biological Process: cGMP biosynthetic process; protein amino acid phosphorylation; signal transduction

Similar Products

Product Notes

The PGCG gucy2g (Catalog #AAA544259) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PGCG can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Confocal Microscopy||1:200 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the PGCG gucy2g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGCG, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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