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PDE7A blocking peptide

PDE7A Peptide

Gene Names
PDE7A; HCP1; PDE7
Applications
Immunodepletion, Immunocompetition
Synonyms
PDE7A; PDE7A Peptide; HCP 1; P2A; PDE 7; PDE1/PDE2 yeast human complement of; Phosphodiesterase 7A; Phosphodiesterase isozyme 7; Rolipram insensitive phosphodiesterase type 7; TM 22 antibody; PDE7A blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
424
Applicable Applications for PDE7A blocking peptide
Immunodepletion, Immunocompetition
Application Notes
Western Blot: 1:500
Immunogen
Synthetic cyclic peptide common to all PDE7A variants
Expression
PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
Molecular Function
3', 5' -cyclic-AMP phosphodiesterase activity
Structure
Interacts with CBFA2T3
Subcellular Location
Isoform PDE7A1 : Cytoplasm degree cytosol, Isoform PDE7A2: Cytoplasm
Preparation and Storage
-20 degree C for long term storage
Related Product Information for PDE7A blocking peptide
Antigenic Blocking Peptide cAMP-specific cyclic nucleotide phosphodiesterase PDE7A3
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
48,828 Da
NCBI Official Full Name
cAMP-specific cyclic nucleotide phosphodiesterase PDE7A3
NCBI Official Synonym Full Names
phosphodiesterase 7A
NCBI Official Symbol
PDE7A
NCBI Official Synonym Symbols
HCP1; PDE7
NCBI Protein Information
high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
UniProt Protein Name
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
UniProt Gene Name
PDE7A
UniProt Entry Name
PDE7A_HUMAN

NCBI Description

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Uniprot Description

PDE7A: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.53; Phosphodiesterase; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 8q13

Cellular Component: cytosol

Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; metal ion binding

Biological Process: cAMP catabolic process; cAMP-mediated signaling

Research Articles on PDE7A

Similar Products

Product Notes

The PDE7A pde7a (Catalog #AAA544224) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PDE7A can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE7A pde7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE7A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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