OASL blocking peptide
OASL Peptide
Gene Names
OASL; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
Applications
Blocking (BL)
Synonyms
OASL; OASL Peptide; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14; 2'-5'-oligoadenylate synthetase-like; OASL blocking peptide
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
514
Applicable Applications for OASL blocking peptide
Blocking (BL)
Application Notes
The peptide is used for blocking the activity of OASL Antibody. It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37 degree C.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
17 amino acids near the amino terminus of human OASL.
Preparation and Storage
Store OASL Peptide at -20 degree C, stable for one year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,942 Da
NCBI Official Full Name
2'-5'-oligoadenylate synthase-like protein isoform a
NCBI Official Synonym Full Names
2'-5'-oligoadenylate synthetase-like
NCBI Official Symbol
OASL
NCBI Official Synonym Symbols
OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
NCBI Protein Information
2'-5'-oligoadenylate synthase-like protein; 2'-5'-OAS-RP; 2'-5'-OAS-related protein; TR-interacting protein 14; thyroid receptor-interacting protein 14; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein
UniProt Protein Name
2'-5'-oligoadenylate synthase-like protein
Protein Family
UniProt Gene Name
OASL
UniProt Synonym Gene Names
TRIP14; 2'-5'-OAS-RP; TR-interacting protein 14; TRIP-14; p59OASL
UniProt Entry Name
OASL_HUMAN
Uniprot Description
OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1.
Protein type: DNA-binding; Nucleolus
Chromosomal Location of Human Ortholog: 12q24.2
Cellular Component: membrane; cytoplasm; nucleolus; cytosol
Molecular Function: DNA binding; double-stranded RNA binding; thyroid hormone receptor binding; ATP binding; 2'-5'-oligoadenylate synthetase activity
Biological Process: negative regulation of viral genome replication; metabolic process; response to virus; cytokine and chemokine mediated signaling pathway; defense response to virus
Research Articles on OASL
Similar Products
Product Notes
The OASL oasl (Catalog #AAA154079) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's OASL can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). The peptide is used for blocking the activity of OASL Antibody. It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37 degree C. Researchers should empirically determine the suitability of the OASL oasl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OASL, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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