NXF3 blocking peptide
NXF3 Blocking Peptide (N-Term)
NCBI and Uniprot Product Information
NCBI Description
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
Uniprot Description
NXF3: May function as a tissue-specific nuclear mRNA export factor. Belongs to the NXF family.
Chromosomal Location of Human Ortholog: Xq22
Cellular Component: cytoplasm; nuclear RNA export factor complex; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus
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Product Notes
The NXF3 nxf3 (Catalog #AAA9230332) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NXF3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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