Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

NUDC blocking peptide

NUDC Antibody (Center) Blocking Peptide

Gene Names
NUDC; HNUDC; MNUDC; NPD011
Synonyms
NUDC; NUDC Antibody (Center) Blocking Peptide; Nuclear migration protein nudC; Nuclear distribution protein C homolog; NUDC blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
331
Cellular Location
Cytoplasm, cytoskeleton. Nucleus. Note: In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern
Tissue Location
Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NUDC blocking peptide
Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
38,243 Da
NCBI Official Full Name
Nuclear migration protein nudC
NCBI Official Synonym Full Names
nuclear distribution C, dynein complex regulator
NCBI Official Symbol
NUDC
NCBI Official Synonym Symbols
HNUDC; MNUDC; NPD011
NCBI Protein Information
nuclear migration protein nudC
UniProt Protein Name
Nuclear migration protein nudC
Protein Family
UniProt Gene Name
NUDC
UniProt Entry Name
NUDC_HUMAN

NCBI Description

This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]

Uniprot Description

NUDC: a cytoskeletal protein that is a component of the dynactin complex. The cytoplasmic dynein/dynactin complex, a minus-end-directed motor, powers various) aspects of mitosis, including establishment of bipolarity, organization of spindle poles, alignment and segregation of chromosomes, as well as regulation of microtubule dynamics. Phosphorylation by PLK1 may play a critical role in cytokinesis.

Protein type: Cell cycle regulation; Cytoskeletal

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: cytoplasm; cytosol; nucleoplasm

Molecular Function: protein binding

Biological Process: cell proliferation; multicellular organismal development; sister chromatid cohesion

Research Articles on NUDC

Similar Products

Product Notes

The NUDC nudc (Catalog #AAA9221399) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NUDC, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.