NOVA1 blocking peptide

NOVA1 Blocking Peptide (Center)

Gene Names

NOVA1; Nova-1

Synonyms

NOVA1; NOVA1 Blocking Peptide (Center); RNA-binding protein Nova-1; Neuro-oncological ventral antigen 1; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; Ventral neuron-specific protein 1; NOVA1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 139-153 of HUMAN NOVA1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

510

Cellular Location

Nucleus.

Tissue Location

Brain.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NOVA1 blocking peptide

May regulate RNA splicing or metabolism in a specific subset of developing neurons.

NCBI and Uniprot Product Information

NCBI GI #

1709303

NCBI GeneID

4857

UniProt Accession #

P51513; Q6B004; A8K0S4; A8K4Q7; D3DS81; D3DS82

Molecular Weight

49,253 Da

NCBI Official Full Name

RNA-binding protein Nova-1

NCBI Official Synonym Full Names

NOVA alternative splicing regulator 1

NCBI Official Symbol

NOVA1

NCBI Official Synonym Symbols

Nova-1

NCBI Protein Information

RNA-binding protein Nova-1

UniProt Protein Name

RNA-binding protein Nova-1

Protein Family

RNA-binding protein

UniProt Gene Name

NOVA1

UniProt Entry Name

NOVA1_HUMAN

NCBI Description

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA splicing

Chromosomal Location of Human Ortholog: 14q

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: RNA binding

Biological Process: locomotory behavior; RNA processing; RNA splicing; synaptic transmission

Research Articles on NOVA1

1. Quantitative proteomic analysis was performed to help elucidate a molecular distinction between glioblastoma and oligodendroglioma; analysis showed HSPB1 and NOVA1 to be discriminating factors.

Similar Products

Product Notes

The NOVA1 nova1 (Catalog #AAA9229610) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NOVA1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Loading...

NOVA1 blocking peptide