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NGDN blocking peptide

NGDN Antibody (Center) Blocking Peptide

Gene Names
NGDN; NGD; LCP5; CANu1; lpd-2; C14orf120
Synonyms
NGDN; NGDN Antibody (Center) Blocking Peptide; Neuroguidin; Centromere accumulated nuclear protein 1; CANu1; EIF4E-binding protein; C14orf120; NGDN blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
315
Cellular Location
Nucleus. Nucleus, nucleolus. Chromosome, centromere. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, filopodium Note: Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NGDN blocking peptide
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
35,250 Da
NCBI Official Full Name
Neuroguidin
NCBI Official Synonym Full Names
neuroguidin
NCBI Official Symbol
NGDN
NCBI Official Synonym Symbols
NGD; LCP5; CANu1; lpd-2; C14orf120
NCBI Protein Information
neuroguidin
UniProt Protein Name
Neuroguidin
Protein Family
UniProt Gene Name
NGDN
UniProt Synonym Gene Names
C14orf120; CANu1
UniProt Entry Name
NGDN_HUMAN

NCBI Description

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]

Uniprot Description

NGDN: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. Belongs to the SAS10 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Translation; Nucleolus

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleolus; small subunit processome

Molecular Function: protein binding

Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Research Articles on NGDN

Similar Products

Product Notes

The NGDN ngdn (Catalog #AAA9221206) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NGDN, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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