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NAPSIN A blocking peptide

NAPSIN A Peptide

Gene Names
NAPSA; KAP; Kdap; NAP1; NAPA; SNAPA
Applications
Immunocompetition, Immunodepletion
Synonyms
NAPSIN A; NAPSIN A Peptide; ASP 4 antibody Aspartyl protease 4; KAP; Kdap; Kidney derived aspartic protease like protein; NAP1; NAPA; NAPSA; Napsin 1; napsin A aspartic peptidase antibody Pronapsin A; SNAPA; TA01/TA02 antibody; NAPSIN A blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
357
Applicable Applications for NAPSIN A blocking peptide
Immunocompetition, Immunodepletion
Application Notes
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 250-300 on human Napsin A protein.
Expression
Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.
Determinant
C-epitope
Molecular Function
aspartic-type endopeptidase activity; peptidase activity
Structure
Belongs to the peptidase A1 family.
Subcellular Location
alveolar lamellar body; Extracellular space; Extracellular vesicular exosome; lysosome
Preparation and Storage
-20 degree C for long term storage
Related Product Information for NAPSIN A blocking peptide
Antigenic Blocking Peptide Napsin A aspartic peptidase C-epitope
May be involved in processing of pneumocyte surfactant precursors

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
45,387 Da
NCBI Official Full Name
napsin A aspartic peptidase, isoform CRA_b
NCBI Official Synonym Full Names
napsin A aspartic peptidase
NCBI Official Symbol
NAPSA
NCBI Official Synonym Symbols
KAP; Kdap; NAP1; NAPA; SNAPA
NCBI Protein Information
napsin-A
UniProt Protein Name
Napsin-A
UniProt Gene Name
NAPSA
UniProt Synonym Gene Names
NAP1; NAPA; ASP4; Asp 4
UniProt Entry Name
NAPSA_HUMAN

NCBI Description

This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]

Uniprot Description

NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.

Protein type: EC 3.4.23.-; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; lysosome

Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity

Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; proteolysis; surfactant homeostasis

Research Articles on NAPSIN A

Similar Products

Product Notes

The NAPSIN A napsa (Catalog #AAA544023) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NAPSIN A can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion. Western Blot: 1:500. Researchers should empirically determine the suitability of the NAPSIN A napsa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAPSIN A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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