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MGAT1 blocking peptide

MGAT1 Antibody (Center) Blocking Peptide

Gene Names
MGAT1; GnTI; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI
Synonyms
MGAT1; MGAT1 Antibody (Center) Blocking Peptide; Alpha-1;3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I; GGNT1; GLCT1; GLYT1; MGAT; MGAT1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
445
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
Appears to be present in all tissues.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MGAT1 blocking peptide
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
50,878 Da
NCBI Official Full Name
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NCBI Official Synonym Full Names
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
NCBI Official Symbol
MGAT1
NCBI Official Synonym Symbols
GnTI; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI
NCBI Protein Information
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
UniProt Protein Name
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
UniProt Gene Name
MGAT1
UniProt Synonym Gene Names
GGNT1; GLCT1; GLYT1; MGAT; GNT-I; GlcNAc-T I
UniProt Entry Name
MGAT1_HUMAN

NCBI Description

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

MGAT1: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Belongs to the glycosyltransferase 13 family.

Protein type: Glycan Metabolism - N-glycan biosynthesis; Transferase; EC 2.4.1.101; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: Golgi membrane; membrane

Molecular Function: acetylglucosaminyltransferase activity; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

Biological Process: carbohydrate metabolic process

Research Articles on MGAT1

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Product Notes

The MGAT1 mgat1 (Catalog #AAA9222122) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MGAT1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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