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MCH-2R blocking peptide

MCH-2R (M332) Peptide

Gene Names
MCHR2; SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2
Applications
Blocking
Purity
Synthetic peptide MCH-2R (M332). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Synonyms
MCH-2R; MCH-2R (M332) Peptide; MCHR2; GPR145; GPRV17; MCH-R2; MCH2; MCH2R; MCHR-2; S643B; SLT; MCH-2R blocking peptide
Ordering
For Research Use Only!
Specificity
This peptide can be used with studies using MBS3002859 MCH-2R (M332) pAb.
Purity/Purification
Synthetic peptide MCH-2R (M332). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
340
Applicable Applications for MCH-2R blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for MCH-2R blocking peptide
Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide, which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
melanin-concentrating hormone receptor 2
NCBI Official Synonym Full Names
melanin concentrating hormone receptor 2
NCBI Official Symbol
MCHR2
NCBI Official Synonym Symbols
SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2
NCBI Protein Information
melanin-concentrating hormone receptor 2
UniProt Protein Name
Melanin-concentrating hormone receptor 2
UniProt Gene Name
MCHR2
UniProt Synonym Gene Names
GPR145; SLT; MCH receptor 2; MCH-R2; MCHR-2; MCH2; MCH2R
UniProt Entry Name
MCHR2_HUMAN

Uniprot Description

MCHR2: Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q16

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on MCH-2R

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Product Notes

The MCH-2R mchr2 (Catalog #AAA3002860) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MCH-2R can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the MCH-2R mchr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCH-2R, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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