MC3 Receptor Blocking Peptide | MC3 blocking peptide

MC3 Receptor Antibody Antigenic Blocking Peptide

Gene Names

MC3R; MC3; OB20; OQTL; BMIQ9; MC3-R

Applications

Immunodepletion, Immunocompetition

Synonyms

MC3 Receptor; MC3 Receptor Antibody Antigenic Blocking Peptide; BMIQ9; MC3; Melanocortin 3 receptor; OB20; Obesity quantitative trait locus; OQTL antibody; MC3 blocking peptide

Ordering
Cat. Num. AAA543976 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Form/Format

Antigenic Blocking Peptide

Concentration

Quantity: 250 ug; Volume: 100 ul (varies by lot)

Sequence Length

360

Applicable Applications for MC3 blocking peptide

Immunodepletion, Immunocompetition

Application Notes

Western Blot: 1:500

Immunogen

Synthetic Peptide

Expression

Brain, placental, and gut tissues.

Determinant

C-epitope

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Structure

Belongs to the G-protein coupled receptor 1 family.

Subcellular Location

Cell membrane, Membrane

Preparation and Storage

-20 degree C for long term storage

Related Product Information for MC3 blocking peptide

Antigenic Blocking Peptide Melanocortin 3 receptor Antibody C-epitope
Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.

NCBI and Uniprot Product Information

NCBI GI #

29373117

NCBI GeneID

4159

UniProt Accession #

P41968; Q4KN27; Q9H517

Molecular Weight

36,043 Da

NCBI Official Full Name

melanocortin 3 receptor

NCBI Official Synonym Full Names

melanocortin 3 receptor

NCBI Official Symbol

MC3R

NCBI Official Synonym Symbols

MC3; OB20; OQTL; BMIQ9; MC3-R

NCBI Protein Information

melanocortin receptor 3

UniProt Protein Name

Melanocortin receptor 3

UniProt Gene Name

MC3R

UniProt Synonym Gene Names

MC3-R

UniProt Entry Name

MC3R_HUMAN

NCBI Description

This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]

Uniprot Description

MC3R: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 20q13.2-q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: melanocortin receptor activity; melanocyte stimulating hormone receptor activity; neuropeptide binding; peptide hormone binding; protein binding

Biological Process: circadian regulation of gene expression; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); homoiothermy; locomotor rhythm; positive regulation of cAMP biosynthetic process; regulation of blood pressure; regulation of heart rate; sodium ion homeostasis

Disease: Body Mass Index Quantitative Trait Locus 9; Mycobacterium Tuberculosis, Susceptibility To

Research Articles on MC3

1. novel data about the structure-function relationship of MC3R, identifying residues important for receptor function; some studied mutations exhibited biased signaling, preferentially activating one intracellular signaling pathway.

Similar Products

MC3 Antibody

Host: Rabbit

Reactivity: Human, Mouse, Rat

Apps: ELISA, Western Blot

Product Notes

The MC3 mc3r (Catalog #AAA543976) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MC3 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Western Blot: 1:500. Researchers should empirically determine the suitability of the MC3 mc3r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MC3 Receptor, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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