MaxiKbeta2 blocking peptide
MaxiKbeta2 (I186) Peptide
Gene Names
KCNMB1; hbeta1; BKbeta1; SLO-BETA; hslo-beta; K(VCA)beta; slo-beta-1; k(VCA)beta-1
Applications
Blocking
Purity
Synthetic peptide MaxiKbeta2 (I186). (Note: the amino acid sequence is proprietary).The purity is >98%.
Synonyms
MaxiKbeta2; MaxiKbeta2 (I186) Peptide; KCNMB 1; KCNMB1; Hbeta1; hslo beta; K(VCA)beta 1; K(VCA)beta; BKbeta; BKbeta1; MaxiKbeta2 blocking peptide
Specificity
This peptide can be used with studies using MBS3013680 MaxiKbeta2 (I186) pAb.
Purity/Purification
Synthetic peptide MaxiKbeta2 (I186). (Note: the amino acid sequence is proprietary).
The purity is >98%.
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
191
Applicable Applications for MaxiKbeta2 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for MaxiKbeta2 blocking peptide
MaxiKbeta subunit 1 consists of two putative transmembrane domains, an extracellular loop containing three consensus sequences for N-linked glycosylation and four cysteine residues that might form disulfide bridges. MaxiKbeta subunit 1, one of four subunits in the MaxiKbeta family, is expressed predominately in smooth muscle tissue but is also found in brain, liver and lymphatic tissues. MaxiKbeta subunit 1 associates with MaxiKalpha to form a calcium-activated potassium channel (also designated MaxiK and BK channel). MaxiKbeta subunit 1 increases the sensitivity of the MaxiKalpha to calcium and voltage. The MaxiKalpha/beta1 channel is the most sensitive of all Maxi channels to calcium. MaxiKbeta plays an important role in vasoregulation by controlling the sensitivity of MaxiK channels to calcium, which leads to the proper amount of arterial relaxation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
calcium-activated potassium channel subunit beta-1
NCBI Official Synonym Full Names
potassium calcium-activated channel subfamily M regulatory beta subunit 1
NCBI Official Symbol
KCNMB1
NCBI Official Synonym Symbols
hbeta1; BKbeta1; SLO-BETA; hslo-beta; K(VCA)beta; slo-beta-1; k(VCA)beta-1
NCBI Protein Information
calcium-activated potassium channel subunit beta-1
UniProt Protein Name
Calcium-activated potassium channel subunit beta-1
UniProt Gene Name
KCNMB1
UniProt Synonym Gene Names
BKbeta; BKbeta1; Hbeta1; Calcium-activated potassium channel subunit beta; Slo-beta
UniProt Entry Name
KCMB1_HUMAN
NCBI Description
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Research Articles on MaxiKbeta2
Similar Products
Product Notes
The MaxiKbeta2 kcnmb1 (Catalog #AAA3013691) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MaxiKbeta2 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the MaxiKbeta2 kcnmb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MaxiKbeta2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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