Map3k2 blocking peptide
Mouse Map3k2 Antibody (N-term) Blocking peptide
Gene Names
Map3k2; Mekk2; Mekk2b; AI585793; 9630061B06Rik
Synonyms
Map3k2; Mouse Map3k2 Antibody (N-term) Blocking peptide; Mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; Mekk2; Map3k2 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of Mouse Map3k2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
619
Cellular Location
Cytoplasm. Nucleus. Note: Upon EGF stimulation, translocates into the nucleus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Map3k2 blocking peptide
Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss- and-run dynamics (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
69,574 Da
NCBI Official Full Name
Mitogen-activated protein kinase kinase kinase 2
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 2
NCBI Official Symbol
Map3k2
NCBI Official Synonym Symbols
Mekk2; Mekk2b; AI585793; 9630061B06Rik
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 2
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 2
UniProt Gene Name
Map3k2
UniProt Synonym Gene Names
Mekk2; MEK kinase 2; MEKK 2
UniProt Entry Name
M3K2_MOUSE
Uniprot Description
MEKK2: a protein kinase of the STE11 family. Phosphorylates and activates MEK5. Involved in growth factor stimulated cell proliferation and differentiation.
Protein type: Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.25; STE group; STE11 family
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus
Molecular Function: MAP kinase kinase kinase activity; protein binding; protein kinase activity; protein kinase binding; receptor signaling protein serine/threonine kinase activity
Biological Process: positive regulation of transcription, DNA-dependent; protein amino acid phosphorylation
Research Articles on Map3k2
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Product Notes
The Map3k2 map3k2 (Catalog #AAA9220296) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Map3k2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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