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LPHN3 blocking peptide

LPHN3 Antibody (N-term) Blocking Peptide

Gene Names
ADGRL3; CL3; LEC3; CIRL3; LPHN3
Synonyms
LPHN3; LPHN3 Antibody (N-term) Blocking Peptide; Latrophilin-3; Calcium-independent alpha-latrotoxin receptor 3; CIRL-3; Lectomedin-3; KIAA0768; LEC3; LPHN3 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
1447
Cellular Location
Cell membrane; Multi-pass membrane protein.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for LPHN3 blocking peptide
May be involved in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
164,580 Da
NCBI Official Full Name
Adhesion G protein-coupled receptor L3
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor L3
NCBI Official Symbol
ADGRL3
NCBI Official Synonym Symbols
CL3; LEC3; CIRL3; LPHN3
NCBI Protein Information
adhesion G protein-coupled receptor L3
UniProt Protein Name
Adhesion G protein-coupled receptor L3
UniProt Gene Name
ADGRL3
UniProt Synonym Gene Names
CIRL-3
UniProt Entry Name
AGRL3_HUMAN

NCBI Description

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

Uniprot Description

latrophilin 3: a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral; GPCR, family 2; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4q13.1

Cellular Component: axon; integral to plasma membrane; intercellular junction

Molecular Function: calcium ion binding; protein binding

Biological Process: neuron migration; synaptogenesis

Research Articles on LPHN3

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Product Notes

The LPHN3 adgrl3 (Catalog #AAA9222764) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LPHN3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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