LLGL1/2 blocking peptide
Bi-Phospho-LLGL1/2 (S653/S649) Antibody Blocking Peptide
Gene Names
LLGL2; HGL; LGL2; Hugl-2
Synonyms
LLGL1/2; Bi-Phospho-LLGL1/2 (S653/S649) Antibody Blocking Peptide; Lethal(2) giant larvae protein homolog 2; HGL; LLGL2; LLGL1/2 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the region of human Phospho-LLGL1/2-S650/S654. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Sequence Length
1020
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for LLGL1/2 blocking peptide
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
lethal(2) giant larvae protein homolog 2 isoform c
NCBI Official Synonym Full Names
LLGL scribble cell polarity complex component 2
NCBI Official Symbol
LLGL2
NCBI Official Synonym Symbols
HGL; LGL2; Hugl-2
NCBI Protein Information
lethal(2) giant larvae protein homolog 2
UniProt Protein Name
Lethal(2) giant larvae protein homolog 2
UniProt Gene Name
LLGL2
UniProt Entry Name
L2GL2_HUMAN
NCBI Description
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Research Articles on LLGL1/2
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Product Notes
The LLGL1/2 llgl2 (Catalog #AAA9231509) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LLGL1/2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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