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LILRB3 blocking peptide

LILRB3 Antibody Antigenic Blocking Peptide

Gene Names
Pirb; Gp91; LIR-3; PIR-B; Lilrb3
Applications
Immunodepletion, Immunocompetition
Synonyms
LILRB3; LILRB3 Antibody Antigenic Blocking Peptide; CD85 antigen like family member A; HL9; IL T5; Immunoglobulin like transcript 5; LIR 3; MGC138403; Monocyte inhibitory receptor HL9; PIRB antibody; LILRB3 blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
841
Applicable Applications for LILRB3 blocking peptide
Immunodepletion, Immunocompetition
Application Notes
Western Blot: 1:500
Immunogen
Synthetic Peptide
Expression
Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
Subcellular Location
Cell membrane, Single-pass type I membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for LILRB3 blocking peptide
Antigenic Blocking Peptide Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93,054 Da
NCBI Official Full Name
leukocyte immunoglobulin-like receptor subfamily B member 3
NCBI Official Synonym Full Names
paired Ig-like receptor B
NCBI Official Symbol
Pirb
NCBI Official Synonym Symbols
Gp91; LIR-3; PIR-B; Lilrb3
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily B member 3
UniProt Protein Name
Leukocyte immunoglobulin-like receptor subfamily B member 3
UniProt Gene Name
Lilrb3
UniProt Synonym Gene Names
Pirb; LIR-3; Leukocyte immunoglobulin-like receptor 3; PIR-B
UniProt Entry Name
LIRB3_MOUSE

Uniprot Description

Pirb: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Protein type: Membrane protein, integral

Cellular Component: integral to membrane; membrane; plasma membrane

Biological Process: adaptive immune response; B cell homeostasis; B cell mediated immunity; cytokine and chemokine mediated signaling pathway; immune system process; myeloid dendritic cell differentiation

Research Articles on LILRB3

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Product Notes

The LILRB3 lilrb3 (Catalog #AAA543934) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LILRB3 can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Western Blot: 1:500. Researchers should empirically determine the suitability of the LILRB3 lilrb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LILRB3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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