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Lgals3 blocking peptide

Mouse Lgals3 Antibody (Center) Blocking Peptide

Synonyms
Lgals3; Mouse Lgals3 Antibody (Center) Blocking Peptide; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; L-34 galactoside-binding lectin; Laminin-binding protein; Lectin L-29; Mac-2 antigen; Lgals3 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
264
Cellular Location
Cytoplasm. Nucleus. Secreted. Note: Secreted by a non-classical secretory pathway and associates with the cell surface
Tissue Location
The highest levels are found in activated macrophages
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Lgals3 blocking peptide
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
27,515 Da
NCBI Official Full Name
Galectin-3
UniProt Protein Name
Galectin-3
UniProt Gene Name
Lgals3
UniProt Synonym Gene Names
Gal-3; CBP 35
UniProt Entry Name
LEG3_MOUSE

Uniprot Description

galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Cell surface; Motility/polarity/chemotaxis; Extracellular matrix

Cellular Component: cell surface; cytoplasm; external side of plasma membrane; extracellular matrix; extracellular space; immunological synapse; membrane; mitochondrial inner membrane; nucleus; proteinaceous extracellular matrix

Molecular Function: advanced glycation end-product receptor activity; chemoattractant activity; disaccharide binding; IgE binding; laminin binding; monosaccharide binding; protein binding

Biological Process: eosinophil chemotaxis; extracellular matrix organization and biogenesis; macrophage chemotaxis; maintenance of protein localization; monocyte chemotaxis; negative regulation of apoptosis; negative regulation of endocytosis; negative regulation of T cell receptor signaling pathway; neutrophil chemotaxis; positive chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of serotonin secretion; regulation of T cell proliferation; skeletal development

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Product Notes

The Lgals3 lgals3 (Catalog #AAA9224210) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lgals3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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