KRTAP1-3 blocking peptide

KRTAP1-3 Antibody (Center) Blocking peptide

• Gene Names: KRTAP1-3; KAP1.2; KAP1.3; KAP1.6; KAP1.9; KAP1.8A; KAP1.8B; KRTAP1.3
• Synonyms: KRTAP1-3; KRTAP1-3 Antibody (Center) Blocking peptide; Keratin-associated protein 1-3; Keratin-associated protein 18; Keratin-associated protein 19; KRTAP1-3 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 177

• Tissue Location: Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for KRTAP1-3 blocking peptide

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.

NCBI and Uniprot Product Information

• NCBI GI #: 74723628
• NCBI GeneID: 81850
• UniProt Accession #: Q8IUG1; Q07628; Q8IUG0; Q9BYS2
• Molecular Weight: 18,184 Da
• NCBI Official Full Name: Keratin-associated protein 1-3
• NCBI Official Synonym Full Names: keratin associated protein 1-3
• NCBI Official Symbol: KRTAP1-3
• NCBI Official Synonym Symbols: KAP1.2; KAP1.3; KAP1.6; KAP1.9; KAP1.8A; KAP1.8B; KRTAP1.3
• NCBI Protein Information: keratin-associated protein 1-3
• UniProt Protein Name: Keratin-associated protein 1-3
• Protein Family: Keratin-associated protein
• UniProt Gene Name: KRTAP1-3
• UniProt Synonym Gene Names: B2B; KAP1.2; KAP1.3; KAP1.8; KAP1.9; KRATP1.9; KRTAP1.8
• UniProt Entry Name: KRA13_HUMAN

NCBI Description

This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]

Uniprot Description

KRTAP1-3: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 1 family. Interacts with hair keratins

Chromosomal Location of Human Ortholog: 17q21.2