KLF14 blocking peptide

KLF14 Blocking Peptide

Cat. Num. AAA9622825

• Gene Names: KLF14; BTEB5
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: KLF14; KLF14 Blocking Peptide; Basic transcription element binding protein 5; Basic transcription element-binding protein 5; BTE binding protein 5; BTE-binding protein 5; BTEB5; KLF 14; KLF14_HUMAN; Krueppel-like factor 14; Kruppel like factor 14; Transcription factor BTEB5; KLF14 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for KLF14 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for KLF14 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 527122127
• NCBI GeneID: 136259
• NCBI Accession #: NP_619638.2
• NCBI GenBank Nucleotide #: NM_138693.3
• UniProt Accession #: Q8TD94; Q19A42; Q19A43; A0A075B756; A4D1N0
• Molecular Weight: 33,124 Da
• NCBI Official Full Name: Krueppel-like factor 14
• NCBI Official Synonym Full Names: Kruppel-like factor 14
• NCBI Official Symbol: KLF14
• NCBI Official Synonym Symbols: BTEB5
• NCBI Protein Information: Krueppel-like factor 14; BTE-binding protein 5; transcription factor BTEB5; basic transcription element-binding protein 5
• UniProt Protein Name: Krueppel-like factor 14
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF14
• UniProt Synonym Gene Names: BTEB5; BTE-binding protein 5
• UniProt Entry Name: KLF14_HUMAN

NCBI Description

This intronless gene encodes a member of the Kruppel-like family of transcription factors. The encoded protein functions as a transcriptional co-repressor, and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression. This gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. [provided by RefSeq, Jul 2013]

Uniprot Description

KLF14: a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2. [provided by RefSeq, Nov 2009]

Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 7q32.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter