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JMJD2D blocking peptide

JMJD2D Antibody Antigenic Blocking Peptide

Gene Names
KDM4D; JMJD2D
Applications
Immunodepletion, Immunocompetition
Synonyms
JMJD2D; JMJD2D Antibody Antigenic Blocking Peptide; JHD3D; JHDM3D; JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D; Kdm4d; Lysine-specific demethylase 4D antibody; JMJD2D blocking peptide
Ordering
For Research Use Only!
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
523
Applicable Applications for JMJD2D blocking peptide
Immunodepletion, Immunocompetition
Application Notes
Western Blot: 1:500
Immunogen
Synthetic Peptide
Molecular Function
Chromatin regulator, Dioxygenase, Oxidoreductase
Structure
Belongs to the JHDM3 histone demethylase family.
Contains 1 JmjC domain.
Contains 1 JmjN domain.
Subcellular Location
Nucleus
Preparation and Storage
-20 degree C for long term storage
Related Product Information for JMJD2D blocking peptide
Antigenic Blocking Peptide Jumonji domain-containing protein 2D Antibody
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
58,603 Da
NCBI Official Full Name
Jumonji domain containing 2D
NCBI Official Synonym Full Names
lysine demethylase 4D
NCBI Official Symbol
KDM4D
NCBI Official Synonym Symbols
JMJD2D
NCBI Protein Information
lysine-specific demethylase 4D
UniProt Protein Name
Lysine-specific demethylase 4D
UniProt Gene Name
KDM4D
UniProt Synonym Gene Names
JHDM3D; JMJD2D
UniProt Entry Name
KDM4D_HUMAN

Uniprot Description

JMJD2D: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Belongs to the JHDM3 histone demethylase family.

Protein type: EC 1.14.11.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: nucleoplasm

Molecular Function: dioxygenase activity; histone demethylase activity; histone demethylase activity (H3-K9 specific); metal ion binding

Biological Process: double-strand break repair via homologous recombination; histone H3-K9 demethylation; regulation of protein amino acid phosphorylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on JMJD2D

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Product Notes

The JMJD2D kdm4d (Catalog #AAA543885) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's JMJD2D can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Western Blot: 1:500. Researchers should empirically determine the suitability of the JMJD2D kdm4d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JMJD2D, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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