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INPP5A blocking peptide

INPP5A Blocking Peptide (C-term)

Gene Names
INPP5A; 5PTASE
Synonyms
INPP5A; INPP5A Blocking Peptide (C-term); Type I inositol 1;5-trisphosphate 5-phosphatase; 5PTase; INPP5A blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 306-320 of HUMAN INPP5A
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
412
Cellular Location
Membrane; Lipid-anchor.
Tissue Location
Brain; high level in Purkinje cells.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for INPP5A blocking peptide
Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
47,820 Da
NCBI Official Full Name
Type I inositol 1,4,5-trisphosphate 5-phosphatase
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase A
NCBI Official Symbol
INPP5A
NCBI Official Synonym Symbols
5PTASE
NCBI Protein Information
type I inositol 1,4,5-trisphosphate 5-phosphatase
UniProt Protein Name
Type I inositol 1,4,5-trisphosphate 5-phosphatase
UniProt Gene Name
INPP5A
UniProt Synonym Gene Names
5PTase
UniProt Entry Name
I5P1_HUMAN

NCBI Description

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]

Uniprot Description

INPP5A: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type I family.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.56; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: plasma membrane

Molecular Function: PH domain binding; protein binding

Biological Process: inositol phosphate metabolic process

Research Articles on INPP5A

Similar Products

Product Notes

The INPP5A inpp5a (Catalog #AAA9229934) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "INPP5A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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