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HS3ST2 blocking peptide

HS3ST2 Antibody (C-term) Blocking Peptide

Gene Names
HS3ST2; 30ST2; 3OST2
Synonyms
HS3ST2; HS3ST2 Antibody (C-term) Blocking Peptide; Heparan sulfate glucosamine 3-O-sulfotransferase 2; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; 3-OST-2; Heparan sulfate 3-O-sulfotransferase 2; h3-OST-2; 3OST2; HS3ST2 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
367
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
Highly expressed in the brain and weakly expressed in the heart, placenta, lung and skeletal muscle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for HS3ST2 blocking peptide
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
41,501 Da
NCBI Official Full Name
Heparan sulfate glucosamine 3-O-sulfotransferase 2
NCBI Official Synonym Full Names
heparan sulfate-glucosamine 3-sulfotransferase 2
NCBI Official Symbol
HS3ST2
NCBI Official Synonym Symbols
30ST2; 3OST2
NCBI Protein Information
heparan sulfate glucosamine 3-O-sulfotransferase 2
UniProt Protein Name
Heparan sulfate glucosamine 3-O-sulfotransferase 2
UniProt Gene Name
HS3ST2
UniProt Synonym Gene Names
3OST2; 3-OST-2; Heparan sulfate 3-O-sulfotransferase 2; h3-OST-2
UniProt Entry Name
HS3S2_HUMAN

NCBI Description

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

HS3ST2: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. Belongs to the sulfotransferase 1 family.

Protein type: Membrane protein, integral; EC 2.8.2.29; Transferase; Glycan Metabolism - heparan sulfate biosynthesis

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: Golgi membrane

Molecular Function: heparin-glucosamine 3-O-sulfotransferase activity; sulfotransferase activity

Biological Process: glycosaminoglycan biosynthetic process

Research Articles on HS3ST2

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Product Notes

The HS3ST2 hs3st2 (Catalog #AAA9228248) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "HS3ST2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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