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GRHL1 blocking peptide

GRHL1 Antibody (Center) Blocking Peptide

Gene Names
GRHL1; MGR; NH32; LBP32; TFCP2L2
Synonyms
GRHL1; GRHL1 Antibody (Center) Blocking Peptide; Grainyhead-like protein 1 homolog; Mammalian grainyhead; NH32; Transcription factor CP2-like 2; Transcription factor LBP-32; LBP32; MGR; TFCP2L2; GRHL1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
618
Cellular Location
Nucleus.
Tissue Location
Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Highly expressed in placental JEG-3 cells and at very low levels in non-steroidogenic cells. No expression detected in adrenal NCI-H295A cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for GRHL1 blocking peptide
Transcription factor. Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed. May play a role in development. May be involved in epidermal differentiation (By similarity). Binds and transactivates the EN1 promoter.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
57,813 Da
NCBI Official Full Name
Grainyhead-like protein 1 homolog
NCBI Official Synonym Full Names
grainyhead like transcription factor 1
NCBI Official Symbol
GRHL1
NCBI Official Synonym Symbols
MGR; NH32; LBP32; TFCP2L2
NCBI Protein Information
grainyhead-like protein 1 homolog
UniProt Protein Name
Grainyhead-like protein 1 homolog
Protein Family
UniProt Gene Name
GRHL1
UniProt Entry Name
GRHL1_HUMAN

NCBI Description

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development. [provided by RefSeq, Jun 2009]

Uniprot Description

GRHL1: Transcription factor. Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed. May play a role in development. May be involved in epidermal differentiation. Binds and transactivates the EN1 promoter. Belongs to the grh/CP2 family. Grainyhead subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasm; Golgi apparatus; intracellular membrane-bound organelle; nucleoplasm; nucleus

Molecular Function: chromatin DNA binding; sequence-specific DNA binding

Biological Process: epidermis development; positive regulation of transcription from RNA polymerase II promoter

Research Articles on GRHL1

Similar Products

Product Notes

The GRHL1 grhl1 (Catalog #AAA9221648) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GRHL1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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