GPCR GPR75 blocking peptide
GPCR GPR75 Peptide
Gene Names
GPR75; GPRchr2; WI31133
Applications
Immunodepletion, Immunocompetition
Synonyms
GPCR GPR75; GPCR GPR75 Peptide; G protein coupled receptor 75; GPR chr2; Gpr75; Probable G protein coupled receptor 75; WI 31133 antibody; GPCR GPR75 blocking peptide
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (varies by lot)
Sequence Length
540
Applicable Applications for GPCR GPR75 blocking peptide
Immunodepletion, Immunocompetition
Application Notes
Confocal Microscopy||1:250
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Western Blot: 1:500
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid reigon 490-540 on human G protein-coupled receptor 75 protein.
Expression
high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium, Also expressed by islet cells (at protein level)
Determinant
C-epitope
Molecular Function
G-protein coupled receptor, Receptor, Transducer
Subcellular Location
Cell membrane, Membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for GPCR GPR75 blocking peptide
Antigenic Blocking Peptide G protein-coupled receptor 75 (GPR75) C-epitope
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
59,359 Da
NCBI Official Full Name
G protein-coupled receptor 75
NCBI Official Synonym Full Names
G protein-coupled receptor 75
NCBI Official Symbol
GPR75
NCBI Official Synonym Symbols
GPRchr2; WI31133
NCBI Protein Information
probable G-protein coupled receptor 75
UniProt Protein Name
Probable G-protein coupled receptor 75
UniProt Gene Name
GPR75
UniProt Entry Name
GPR75_HUMAN
NCBI Description
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]
Uniprot Description
GPR75: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 2p16
Cellular Component: integral to plasma membrane
Molecular Function: C-C chemokine receptor activity; G-protein coupled receptor activity
Biological Process: cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway
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Product Notes
The GPCR GPR75 gpr75 (Catalog #AAA543784) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GPCR GPR75 can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Confocal Microscopy||1:250 Immunocytochemistry: 1:250 Immunofluorescence: 1:250 Immunohistochemistry: 1:250 Western Blot: 1:500. Researchers should empirically determine the suitability of the GPCR GPR75 gpr75 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPCR GPR75, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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