FABP3 blocking peptide

FABP3 Antibody (N-term) Blocking Peptide

• Gene Names: FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP
• Synonyms: FABP3; FABP3 Antibody (N-term) Blocking Peptide; Fatty acid-binding protein; heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP; FABP11; FABP3 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human FABP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 133

• Cellular Location: Cytoplasm.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for FABP3 blocking peptide

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

NCBI and Uniprot Product Information

• NCBI GI #: 119802
• NCBI GeneID: 2170
• UniProt Accession #: P05413; Q5VV93; Q99957; B2RAB6
• Molecular Weight: 14,858 Da
• NCBI Official Full Name: Fatty acid-binding protein, heart
• NCBI Official Synonym Full Names: fatty acid binding protein 3
• NCBI Official Symbol: FABP3
• NCBI Official Synonym Symbols: MDGI; FABP11; H-FABP; M-FABP; O-FABP
• NCBI Protein Information: fatty acid-binding protein, heart
• UniProt Protein Name: Fatty acid-binding protein, heart
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP3
• UniProt Synonym Gene Names: FABP11; MDGI; H-FABP; MDGI; M-FABP
• UniProt Entry Name: FABPH_HUMAN

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot Description

FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: cytosol; extracellular space

Molecular Function: cytoskeletal protein binding; protein binding

Biological Process: cholesterol homeostasis; negative regulation of cell proliferation; phospholipid homeostasis; regulation of fatty acid oxidation; triacylglycerol catabolic process