DUSP15 blocking peptide

DUSP15 Antibody (N-term) Blocking Peptide

• Gene Names: DUSP15; VHY; C20orf57
• Synonyms: DUSP15; DUSP15 Antibody (N-term) Blocking Peptide; Dual specificity protein phosphatase 15; VH1-related member Y; Vaccinia virus VH1-related dual-specific protein phosphatase Y; C20orf57; VHY; DUSP15 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human DUSP15. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
• Sequence Length: 295

• Cellular Location: Cytoplasm.
• Tissue Location: Highly expressed in testis.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 30316387
• NCBI GeneID: 128853
• UniProt Accession #: Q9H1R2; Q5QP62; Q5QP63; Q5QP65; Q6PGN7; Q8N826; Q9BX24; A6NH79; A8MVC8
• Molecular Weight: 14,721 Da
• NCBI Official Full Name: Dual specificity protein phosphatase 15
• NCBI Official Synonym Full Names: dual specificity phosphatase 15
• NCBI Official Symbol: DUSP15
• NCBI Official Synonym Symbols: VHY; C20orf57
• NCBI Protein Information: dual specificity protein phosphatase 15
• UniProt Protein Name: Dual specificity protein phosphatase 15
• Protein Family: Dual specificity protein phosphatase
• UniProt Gene Name: DUSP15
• UniProt Entry Name: DUS15_HUMAN

NCBI Description

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Description

DUSP15: belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.16; Protein phosphatase, dual-specificity; EC 3.1.3.48

Chromosomal Location of Human Ortholog: 20q11.21

Molecular Function: protein binding

Biological Process: positive regulation of JNK cascade; regulation of cell proliferation; transforming growth factor beta receptor signaling pathway