CNPY3 blocking peptide

CNPY3 Antibody (N-term) Blocking Peptide

• Gene Names: CNPY3; CAG4A; ERDA5; TNRC5; PRAT4A
• Synonyms: CNPY3; CNPY3 Antibody (N-term) Blocking Peptide; Protein canopy homolog 3; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein; CTG4A; ERDA5; PRAT4A; TNRC5; CNPY3 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 278

• Cellular Location: Endoplasmic reticulum.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for CNPY3 blocking peptide

Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 74752319
• NCBI GeneID: 10695
• UniProt Accession #: Q9BT09; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9P0F2
• Molecular Weight: 5,773 Da
• NCBI Official Full Name: Protein canopy homolog 3
• NCBI Official Synonym Full Names: canopy FGF signaling regulator 3
• NCBI Official Symbol: CNPY3
• NCBI Official Synonym Symbols: CAG4A; ERDA5; TNRC5; PRAT4A
• NCBI Protein Information: protein canopy homolog 3
• UniProt Protein Name: Protein canopy homolog 3
• Protein Family: Protein canopy
• UniProt Gene Name: CNPY3
• UniProt Synonym Gene Names: CTG4A; ERDA5; PRAT4A; TNRC5
• UniProt Entry Name: CNPY3_HUMAN

NCBI Description

This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]

Uniprot Description

TNRC5: Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: endoplasmic reticulum lumen

Biological Process: toll-like receptor signaling pathway