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CLIP3 blocking peptide

CLIP3 Antibody (C-term) Blocking peptide

Gene Names
CLIP3; RSNL1; CLIPR59; CLIPR-59
Synonyms
CLIP3; CLIP3 Antibody (C-term) Blocking peptide; CAP-Gly domain-containing linker protein 3; Cytoplasmic linker protein 170-related 59 kDa protein; CLIP-170-related 59 kDa protein; CLIPR-59; CLIPR59; CLIP3 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
547
Cellular Location
Cell membrane; Lipid-anchor. Cytoplasm. Golgi apparatus, Golgi stack. Note: Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CLIP3 blocking peptide
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
59,560 Da
NCBI Official Full Name
CAP-Gly domain-containing linker protein 3
NCBI Official Synonym Full Names
CAP-Gly domain containing linker protein 3
NCBI Official Symbol
CLIP3
NCBI Official Synonym Symbols
RSNL1; CLIPR59; CLIPR-59
NCBI Protein Information
CAP-Gly domain-containing linker protein 3
UniProt Protein Name
CAP-Gly domain-containing linker protein 3
UniProt Gene Name
CLIP3
UniProt Synonym Gene Names
CLIPR59; CLIP-170-related 59 kDa protein; CLIPR-59
UniProt Entry Name
CLIP3_HUMAN

NCBI Description

This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

CLIPR-59: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: cytosol; early endosome membrane; lipid raft; plasma membrane; recycling endosome membrane; trans-Golgi network; trans-Golgi network membrane

Molecular Function: microtubule binding

Biological Process: fat cell differentiation; negative regulation of microtubule polymerization; peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; positive regulation of apoptosis; positive regulation of endocytosis; positive regulation of protein amino acid phosphorylation

Research Articles on CLIP3

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Product Notes

The CLIP3 clip3 (Catalog #AAA9218118) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CLIP3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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