Cebpb-S105 Blocking Peptide | Cebpb blocking peptide
Rat-Cebpb-S105 Blocking Peptide
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the transcription factor family whose members contain a basic leucine-zipper domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. The encoded protein plays important roles in several cellular processes and in various diseases, including regulating cell proliferation, differentiation, apoptosis and neuroinflammation, and being involved in brain injury and inflammatory progression. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with different cellular localizations and distinct biological functions. [provided by RefSeq, Sep 2014]
Uniprot Description
C/EBP-beta: a bZIP transcription factor which can form homodimers or heterodimers with the related proteins CEBP-alpha, -delta and -gamma. Involved in immune and inflammatory responses. Specifically binds to regulatory regions of genes encoding IL-6, other cytokines and several acute-phase proteins. There are two forms of C/EBPbeta, the 38kDa liver activating protein (LAP) and the 20kDa liver inhibitory protein (LIP) which may be products of alternative translation. LAP is a transcriptional activator while LIP may inhibit C/EBPbeta transcriptional activity. Phosphorylated and activated by ERK1/2.
Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor
Cellular Component: cytoplasm; nuclear chromatin; nuclear matrix; nucleoplasm; nucleus
Molecular Function: chromatin binding; DNA binding; glucocorticoid receptor binding; histone acetyltransferase binding; histone deacetylase binding; kinase binding; protein binding; protein heterodimerization activity; protein homodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription factor binding
Biological Process: brown fat cell differentiation; defense response to bacterium; embryonic placenta development; fat cell differentiation; granuloma formation; liver development; mammary gland epithelial cell proliferation; memory; negative regulation of neuron apoptosis; negative regulation of T cell proliferation; negative regulation of transcription, DNA-dependent; neuron differentiation; ovarian follicle development; positive regulation of fat cell differentiation; positive regulation of interleukin-4 production; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of interleukin-6 biosynthetic process; regulation of osteoclast differentiation; regulation of transcription, DNA-dependent; response to lipopolysaccharide
Research Articles on Cebpb
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Product Notes
The Cebpb cebpb (Catalog #AAA9229334) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cebpb-S105, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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