CD99L2 blocking peptide

CD99L2 Antibody (Center) Blocking peptide

• Gene Names: CD99L2; CD99B; MIC2L1
• Synonyms: CD99L2; CD99L2 Antibody (Center) Blocking peptide; CD99 antigen-like protein 2; MIC2-like protein 1; CD99; MIC2L1; CD99L2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 262

• Cellular Location: Cell membrane; Single-pass type I membrane protein; Extracellular side. Cell junction
• Tissue Location: Expressed in many tissues, with low expression in thymus.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for CD99L2 blocking peptide

Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 71067336
• NCBI GeneID: 83692
• NCBI Accession #: NP_113650.2
• NCBI GenBank Nucleotide #: NM_031462.3
• UniProt Accession #: Q8TCZ2; Q8TAW2; Q8TCZ0; Q8TCZ1; Q9BQG9; A8K2D5; A8K5R0; B3KWG2; B4DDL7; E7EMK5; E9PD27
• Molecular Weight: 20,032 Da
• NCBI Official Full Name: CD99 antigen-like protein 2 isoform 1
• NCBI Official Synonym Full Names: CD99 molecule like 2
• NCBI Official Symbol: CD99L2
• NCBI Official Synonym Symbols: CD99B; MIC2L1
• NCBI Protein Information: CD99 antigen-like protein 2
• UniProt Protein Name: CD99 antigen-like protein 2
• Protein Family: CD99 antigen-like protein
• UniProt Gene Name: CD99L2
• UniProt Synonym Gene Names: MIC2L1
• UniProt Entry Name: C99L2_HUMAN

NCBI Description

This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

CD99L2: Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Homophilic adhesion molecule, but these interactions may not be required for cell aggregation. Belongs to the CD99 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: focal adhesion

Molecular Function: protein binding