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CAPN11 blocking peptide

CAPN11 Antibody (Center) Blocking peptide

Gene Names
CAPN11; calpain11
Synonyms
CAPN11; CAPN11 Antibody (Center) Blocking peptide; Calpain-11; 3422-; Calcium-activated neutral proteinase 11; CANP 11; CAPN11 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of CAPN11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
739
Cellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome
Tissue Location
Highest expression in testis.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CAPN11 blocking peptide
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
84,423 Da
NCBI Official Full Name
Calpain-11
NCBI Official Synonym Full Names
calpain 11
NCBI Official Symbol
CAPN11
NCBI Official Synonym Symbols
calpain11
NCBI Protein Information
calpain-11
UniProt Protein Name
Calpain-11
Protein Family
UniProt Gene Name
CAPN11
UniProt Synonym Gene Names
CANP 11
UniProt Entry Name
CAN11_HUMAN

NCBI Description

Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008]

Uniprot Description

CAPN11: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Belongs to the peptidase C2 family.

Protein type: EC 3.4.22.-; Protease

Chromosomal Location of Human Ortholog: 6p12

Cellular Component: cytoplasm

Molecular Function: peptidase activity

Research Articles on CAPN11

Similar Products

Product Notes

The CAPN11 capn11 (Catalog #AAA9220260) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CAPN11, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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